4 ECTS credits
100 h study time
Offer 1 with catalog number 4023308DNR for all students in the 2nd semester
at
a (D) Master - preliminary level.
- Semester
- 2nd semester
- Enrollment based on exam contract
- Impossible
- Grading method
- Grading (scale from 0 to 20)
- Can retake in second session
- Yes
- Taught in
- English
- Faculty
- Faculty of Sciences and Bioengineering Sciences
- Department
- Faculty of Sciences and Bioengineering Sciences
- Educational team
- Stefan Weckx
(course titular)
- Activities and contact hours
-
13 contact hours Lecture
13 contact hours Seminar, Exercises or Practicals
- Course Content
This course starts with an introduction to molecular biology and genetics, knowledge that is needed to understand the concepts and technologies discussed in this course. Next, second and third generation DNA sequencing methods will be discussed, including advantages and disadvantages and their mutual comparison. Hereafter, an introduction to bioinformatics will follow, together with an overview of the most current biological databases. Focus will be on searching those databases using text-based information. Subsequently, principles about DNA and protein sequence-based searches using sequence alignment programmes will be discussed. Next, focus will be on strategies in (meta)genomics and (meta)transcriptomics. Sequence data analysis will be performed hands-on using the scientific workflow platform Galaxy.
- Course material
- Digital course material (Required) : PowerPoint slides will be made available
- Additional info
.
- Learning Outcomes
-
general competencies
The students are able to:
- Discuss the principles of second and third generation sequencing methods;
- Compare the sequencing methods, thereby indicating the strengths and weaknesses;
- Discuss how second and third generation sequencing methods can be applied in (meta)genomics and (meta)transcriptomics;
- Discuss which information is stored in the most common biological databanks;
- Search and retrieve information from the most common biological databanks and platforms using text and sequence data;
- Analyse sequence data using a scientific workflow platform.
- Grading
-
The final grade is composed based on the following categories:
Oral Exam determines 100% of the final mark.
Within the Oral Exam category, the following assignments need to be completed:
- oral exam with written prepara
with a relative weight of 100
which comprises 100% of the final mark.
- Additional info regarding evaluation
The evaluation is based on an oral exam with written preparation
- Allowed unsatisfactory mark
- The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.
Academic context
This offer is part of the following study plans:
Master of Chemistry: Chemical Theory, (Bio)Molecular Design and Synthesis