3 ECTS credits
78 h study time

Offer 1 with catalog number 4021494DNR for all students in the 2nd semester at a (D) Master - preliminary level.

Semester
2nd semester
Enrollment based on exam contract
Impossible
Grading method
Grading (scale from 0 to 20)
Can retake in second session
Yes
Enrollment Requirements
Registration for this course is possible if the student is registered for 'Biochemistry'.
Taught in
English
Partnership Agreement
Under interuniversity agreement for degree program
Faculty
Faculty of Science and Bio-engineering Sciences
Department
Bio-Engineering Sciences
Educational team
Han Karel Remaut (course titular)
Activities and contact hours

26 contact hours Lecture
Course Content

The course looks at how proteins, starting from their unique sequences, fold into 3D structures that are build to perform dedicated biological functions:

  • enzymatic catalysis
  • molecular recognition
  • transport
  • signal transduction
  • molecular motors
  • structural scaffolding

Students will gain an advanced insight into structural buildup of proteins and the ways in which this directs protein function and how genetic disorders can result in protein malfunction and disease. In addition, students will get introduced to methods to study protein structure and learn how to retrieve and handle structural information from protein structure databases.

Additional info

Students need to have had the equivalent of the course Biochemistry.

Learning Outcomes

General competencies

Students will understand the molecular and structural principles that determine protein function and malfunction in: enzymatic catalysis, molecular recognition, transport, signal transduction, molecular motors, and structural scaffolding.

Students will be able to understand and analyse protein structures from standard representations used in scientific literature. They will able to analyse functional implications of protein structural information and critically assess scientific literature reporting such information.

Grading

The final grade is composed based on the following categories:
Other Exam determines 100% of the final mark.

Within the Other Exam category, the following assignments need to be completed:

  • Other exam with a relative weight of 1 which comprises 100% of the final mark.

Additional info regarding evaluation

None

Allowed unsatisfactory mark
The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context

This offer is part of the following study plans:
Master of Molecular Biology: Standaard traject
Master of Biology: Molecular and Cellular Life sciences