3 ECTS credits
78 h study time

Offer 1 with catalog number 4021485FNR for all students in the 1st semester at a (F) Master - specialised level.

Semester
1st semester
Enrollment based on exam contract
Impossible
Grading method
Grading (scale from 0 to 20)
Can retake in second session
Yes
Taught in
English
Partnership Agreement
Under interuniversity agreement for degree program
Faculty
Faculty of Science and Bio-engineering Sciences
Department
Bio-Engineering Sciences
Educational team
Carl De Trez (course titular)
Activities and contact hours

26 contact hours Lecture
Course Content

The lecture series on “Cell Biology and Cell Signaling” will give an overview on different structures and functions of the cells with a special emphasis on how cells from a living organism can integrate multiple extracellular signals and transmit them to specific targets in order to mount appropriate physiological responses. It will also bring some insights on how deregulation of these specialized signaling pathways can lead to pathology and diseases. More specifically the course will:

  1. Introduce the general features of cell structure and functions with a special emphasis on how cells communicate/signal to each other.
  2. Define the mechanisms by which these signals are integrated and transmitted to specific targets within the cell.
  3. Illustrate the differences and similarities between these mechanisms using examples of key signaling molecules and associated pathways implicated in physiological responses, such as growth, apoptosis and inflammation.
  4. Provide a basis to understand how deregulation of physiological signaling cascades can lead to disease development, such as cancer and auto-immune diseases.
  5. Give insight into the experimental methods used for studying cell biology and signalling.
Additional info

Slides available.

Learning Outcomes

General competencies

These are the learning outcomes for the students:

  1. Describe the different structures of a cell and their assocaited functions.
  2. Provide the various types of signalling molecules including receptors, adapter proteins, second messengers, kinases and phosphatases.
  3. Understand how the physical properties of signaling molecules influence their behaviour.
  4. Describe the major intracellular signaling pathways in cells and have an understanding of their complexity and the interactions between them.
  5. Provide an understanding of the link between extracellular signals and intracellular events, including the regulation of gene expression and cellular process.
  6. Discuss the relevance of cell signaling in a variety of physiological and pathological situations.
  7. Possess an overview of the experimental techniques associated with the study of cell biology and cell signaling.

Grading

The final grade is composed based on the following categories:
Other Exam determines 100% of the final mark.

Within the Other Exam category, the following assignments need to be completed:

  • Other exam with a relative weight of 1 which comprises 100% of the final mark.

Additional info regarding evaluation

The evaluation for this course consists of a question related to the content of the course: 20 mins of preparation on the day of the exam followed by a 20 min discussion with the lecturer.

Allowed unsatisfactory mark
The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context

This offer is part of the following study plans:
Master of Molecular Biology: Standaard traject
Master of Biology: Molecular and Cellular Life sciences