6 ECTS credits
180 h study time

Offer 1 with catalog number 4017251DNR for all students in the 1st semester at a (D) Master - preliminary level.

Semester
1st semester
Enrollment based on exam contract
Impossible
Grading method
Grading (scale from 0 to 20)
Can retake in second session
Yes
Enrollment Requirements
Registration for Modelling Physiological Systems is allowed if one is registered for or has successfully accomplished Quantitative Cell Biology and From Genome to Organism.
Taught in
English
Partnership Agreement
Under interuniversity agreement for degree program
Faculty
Faculty of Engineering
Department
Electronics and Informatics
Educational team
Johan STIENS (course titular)
Eowyn VAN WITTENBERGHE
Benyameen KEELSON
Panagiotis GONIDAKIS
Activities and contact hours
36 contact hours Lecture
24 contact hours Seminar, Exercises or Practicals
12 contact hours Independent or External Form of Study
Course Content
- H0: Introduction to physiological systems 

- H1: Componenten & Mechanisms of physiological systems       

        * ATP --> ADP conversion

        * Extensive versus intensive variables

        * recap of thermodynamics

- H2 : Transport processes

- H3 Cel membrane potential: at equilibrium

- H4 Action potentails

       * basics

       * Communication between neurons

- H5 Movement

- H6: Vegetative integration

- H7: Heart en blood circulation: HEART

- H8: Heart en blood circulation: BLOOD CIRCULATION

- H9: Digestion

- H10: Metabolism en Temperature regulation

- H11: Respiratory system

- H12: Renal physiology  

- H13: Sensory systems

   a) Sensory General b) Somato c) Hearing d) Vision e) Propio
Course material
Course text (Required) : Modelling of Physiological Systems, syllabus
Digital course material (Required) : Powerpoint presentation
Handbook (Recommended) : Review of Medical Physiology, William F Ganong, 25de, Lange Medical Books, 9780071825108, 2015
Handbook (Recommended) : Principles of Neural Science, E. Kandel; J. Schwarz; T. Jessell, 5de, Appleton & Lange, 9780071390118, 2012
Additional info

Cuurse lectured during the first semester.
WPO are organized in Etterbeek, partim in Jette, occasionally in Gent.

Responsible lecturer @ VUB: Prof. Johan Stiens
Responsible lecturer @  UGent: Prof. Patrick Segers
Most chapters are available in a syllabus format. Some chapters are available in a powerpoint presentation.

Learning Outcomes

Algemene competenties

The aim of the course is to familiarise the student with human physiology in general and physiological systems in particular, with attention to biological control and regulation mechanisms. The organism is studied on cellular and organ level, as well as on an integrated level. There is attention for transport physics and modelling techniques applied to physiological systems.

KNOWLEDGE OF: basic knowledge of physiology; action potentials, ion channels; force-length-frequency relation; pressure-volume relations, contractility, preload and afterload; pressure-diameter relation, visco-elasticity, impedance; lumped parameter models; arterial pressure wave reflection; heart-arterial coupling; kinetic modelling, osmolarity, convection, diffusion; perfusion, gas transport, disscociation curves; wave intensity analysis.

ACQUIRED INSIGHTS: propagation of electrical signals and communication between cells; insight in the visual system, processing of visual stimuli in the brain into an image; function of individual muscle cells, experimental models; anatomy and function of the heart; assessment of the heart as a pump; mechanical behaviour of blood vessels and quantification of mechanical properties; generation of arterial blood pressure and flow and contribution of the heart and the arteries herein; anatomy and function of the kidney, control mechanisms; (modelling of) mechanics of and gas exchange in the lung; anatomy of the brain

ACQUIRED SKILLS

search of scientific, biomedically oriented material (Pubmed, web of science) through project work, processing of this information into a scientific report and oral communication of these results in a (powerpoint) presentation
analysis and schematizing of physiological processes
analysis of hemodynamic data (arterial pressure and flow, ventricular pressure and volume) and quantification of systolic function, system analysis of the arterial system, quantification of the interaction between the heart and the aretrial system (via spreadsheet and Matlab applications)

This course contributes to the following programme outcomes of the Master of Science in Biomedical Engineering:

MA_A:  KNOWLEDGE ORIENTED COMPETENCES

1. exact sciences with the specificity of their application to engineering
3. the advanced methods and theories to schematize and model complex problems or processes
4. reformulate complex engineering problems in order to solve them (simplifying assumptions, reducing complexity)
7. present and defend results in a scientifically sound way, using contemporary communication tools, for a national as well as for an international professional or lay audience
11. think critically about and evaluate projects, systems and processes, particularly when based on incomplete, contradictory and/or redundant information

MA_B: ATTITUDE

13. a critical attitude towards one’s own results and those of others
16. an attitude of life-long learning as needed for the future development of his/her career

MA_C: SPECIFIC BIOMEDICAL KNOWLEDGE

17. Knowledge of medical sciences to a level that is relevant to function within the context of biomedical technology.
19. To have knowledge of and insight in the role and possibilities of technology in the prevention, diagnosis and treatment of disease, matching the needs of the patient and health care provider.

 

 

Grading

The final grade is composed based on the following categories:
Oral Exam determines 65% of the final mark.
PRAC Report determines 10% of the final mark.
SELF Presentation determines 25% of the final mark.

Within the Oral Exam category, the following assignments need to be completed:

  • Exam with a relative weight of 1 which comprises 65% of the final mark.

Within the PRAC Report category, the following assignments need to be completed:

  • Report Lab with a relative weight of 1 which comprises 10% of the final mark.

Within the SELF Presentation category, the following assignments need to be completed:

  • Evaluation with a relative weight of 1 which comprises 25% of the final mark.

    Note: Non period-bound evaluation counts for 30% of the total score.

Additional info regarding evaluation

Oral examination: Students get a few questions about the content of the course with a very small moment to consult the course material. After this small inspection moment, the student prepare their answers in a closed book framework. Finally oral discussion with the examinator.

Some WPO assignments will be prepared in group and evaluated as a group work. Afterwards an oral discussion about the written report will take place on an individual base. Course and report material may be consulted.

The project assignments will be prepared individually and presented with a slide presentation.

 

Academic context

This offer is part of the following study plans:
European Master of Photonics: Standaard traject