9 ECTS credits
270 u studietijd

Aanbieding 1 met studiegidsnummer 4023284DNR voor alle studenten in het 1e semester met een inleidend master niveau.

Semester
1e semester
Inschrijving onder examencontract
Niet mogelijk
Beoordelingsvoet
Beoordeling (0 tot 20)
2e zittijd mogelijk
Ja
Onderwijstaal
Engels
Onder samenwerkingsakkoord
Onder interuniversitair akkoord mbt. opleiding
Faculteit
Faculteit Wetenschappen en Bio-ingenieurswetensch.
Verantwoordelijke vakgroep
Faculteit Wetenschappen en Bio-ingenieurswetensch.
Externe partnerinstelling(en)
Universiteit Gent
Onderwijsteam
Frank Vanhaecke (titularis)
Onderdelen en contacturen
0 contacturen Exam
68 contacturen Lecture
Inhoud

XRF/XAS

  • Interactions of X-rays with matter
  • Properties of conventional X-ray and synchrotron radiation (SR) sources
  • Quantitative methods in (SR)XRF analysis
  • X-ray Absorption Near Edge Structure (XANES) spectroscopy: theory, instrumentation and applications
  • Extended X-ray Absorption Fine Structure (EXAFS) spectroscopy: theory, instrumentation and applications
  • Scanning X-ray micro- and nano-analysis using synchrotron radiation
  • X-ray fluorescence microtomography: theory, instrumentation and applications
  • Confocal X-ray fluorescence imaging

ICP-MS

  • Introduction to the basic operation principles of the quadrupole filter, sector-field mass spectrometer and time-of-flight analyzer
  • Basic operation principles of ICP-mass spectrometry (ICP-MS)
  • Figures of merit of ICP-MS
  • Spectral interferences
  • Resolution of spectral interferences (physical & chemical resolution)
  • Non-spectral interferences
  • Calibration approaches (including isotope dilution)
  • Alternative sample introduction approaches (including aerosol desolvation, electrothermal vaporization, laser ablation)
  • Advanced ICP-MS applications
  • Ultra-trace elemental analysis
  • Elemental speciation (via hyphenation of HPLC, GC or CE with ICP-MS)
  • Spatially resolved analysis via LA-ICP-MS (including depth profiling analysis & elemental bio-imaging)
  • Single-event ICP-MS (single-particle and single-cell analysis)
  • Tracer experiments with enriched stable isotopes
  • Isotopic analysis of elements with radiogenic isotopes (Sr and Pb isotopic analysis for geochronological dating and provenance determination)
  • Multi-collector ICP-mass spectrometry (including a comparison with thermal ionization mass spectrometry – TIMS)

Surface Analysis

  1. General introduction on surfaces
  • Why study nanomaterials and surfaces?
  • Which information do we obtain?
  1. Methods based on electron interaction
  • Interaction of electrons with matter
  • Overview of techniques based on electron interaction
  • Transmission electron microscopy (TEM) and electron energy loss spectroscopy (EELS)
  • Scanning electron microscopy (SEM, SEM-EDS, SEM-WDS)
  • Auger electron spectroscopy (AES, SAM)
  1. Methods based on photon interaction
  • Interaction of photons with matter
  • Overview of techniques based on photon interaction
  • X-ray photoelectron spectroscopy (XPS)
  • X-ray excited optical luminescence (XEOL and XEOM)
  1. Methods based on ion interaction
  • Interactions of ions with matter
  • Overview of techniques based on ion interaction
  • Secondary ion mass spectrometry (SIMS)
  • Rutherford backscattering (RBS)
  • Particle Induced X-ray Emission (PIXE)
  1. Local probe methods
  •  
  • Scanning probe microscopy (SMP)
  • Scanning force microscopy (SFM)
  • Scanning tunneling microscopy (STM)
  • Atomic force microscopy (AFM)
Bijkomende info

Introduction to the principles of various (synchrotron) X-ray excitation based spectroscopic, mass spectrometers, ICP-mass spectrometry and micro/nano-imaging and surface analysis techniques and their application in the fields of analytical chemistry, geo- and environmental science and materials chemistry. The appearance and origin of spectral and non-spectral interferences is covered and approaches for overcoming the bias thus introduced are discussed.

This course aims at understanding the principles of these techniques together with their capacities in various types of applications. The modules (1) XRF/XAS, (2) ICP-MS and (3) surface analysis are accessible as Advanced Topics in Chemistry.

References

Inductively Coupled Plasma Mass Spectrometry Handbook, ed. S.M. Nelms, Blackwell Publishing, 2005, ISBN 978-1-405-10916.

Inductively Coupled Plasma Spectrometry and its Applications, 2nd edition, ed. S.J. Hill, Blackwell Publishing, 2007, ISBN ISBN: 978-1-405-13594-8.

Isotopic Analysis – Fundamentals and Applications using ICP-MS, eds. F. Vanhaecke and P. Degryse, Wiley-VCH, 2012, ISBN: 978-3-527-65050-7.

Practical Guide to ICP-MS: A Tutorial for Beginners, 3rd edition, R. Thomas, 2013, CRC Press, ISBN 978-1-46655-543-3.

Sector Field Mass Spectrometry for Elemental and Isotopic Analysis, eds. T. Prohaska, J. Irrgeher, A. Zitek and N. Jakubowski, Royal Society of Chemistry, 2015, ISBN: 978-1-84973-392-2.

 

Leerresultaten

general competencies

  • The student has an overview of the principles of the relevant X-ray spectroscopic and imaging methods, their application area, capabilities and limitations.
  • The student has gained a profound insight into the basic operating principles of several types of ICP-mass spectrometers and their capabilities and limitations.
  • The student has an overview of methods for the chemical characterization of nanomaterials and surfaces, their application area, capabilities and limitations.
  • The student is aware of and can explain the basic operating principles of analytical instrumentation for chemical surface analysis.
  • The student is capable of suggesting and appropriate analytical technique for a given chemical problem in this context.

Beoordelingsinformatie

De beoordeling bestaat uit volgende opdrachtcategorieën:
Examen Schriftelijk bepaalt 100% van het eindcijfer

Binnen de categorie Examen Schriftelijk dient men volgende opdrachten af te werken:

  • written met een wegingsfactor 100 en aldus 100% van het totale eindcijfer.

Aanvullende info mbt evaluatie

Written examination. The examination consists of overview questions, more detailed questions on specific course subjects and questions aiming at assessing the student´s understanding of the matter. Evaluate the understanding of basic concepts and being able to apply them in concrete problem cases. Exercises are also included in the theoretical exam

Written exam: 100% (each part (XRF/XAS, ICP-MS and Surface Analysis) contribute an equal share)

Toegestane onvoldoende
Kijk in het aanvullend OER van je faculteit na of een toegestane onvoldoende mogelijk is voor dit opleidingsonderdeel.

Academische context

Deze aanbieding maakt deel uit van de volgende studieplannen:
Master of Chemistry: Analytical and Environmental Chemistry (enkel aangeboden in het Engels)