5 ECTS credits
125 h study time

Offer 1 with catalog number 1016536BNR for all students in the 1st semester at a (B) Bachelor - advanced level.

Semester
1st semester
Enrollment based on exam contract
Impossible
Grading method
Grading (scale from 0 to 20)
Can retake in second session
Yes
Enrollment Requirements
Om een inschrijving te kunnen nemen voor 'Biochemie: Biomoleculen en Metabolisme' moet men : Geslaagd zijn voor ‘Algemene en anorganische chemie’ en ‘Algemene en anorganische chemie practicum’ EN moet men geslaagd of ingeschreven zijn voor ‘Biochemie practicum’ EN moet men geslaagd of ingeschreven zijn voor alle vakken van het eerste jaar bachelor Farmaceutische Wetenschappen OF moet men ingeschreven zijn in de verkorte bachelor FW en voor deze groep studenten geldt ‘Biochemie practicum’ als CO.
Taught in
Dutch
Faculty
Faculteit Geneeskunde en Farmacie
Department
Pathology/molecular and cellular medicine
Educational team
Mark Van De Casteele (course titular)
Activities and contact hours
40 contact hours Lecture
Course Content

In a first part, Biochemistry I-‘Biomolecules’, the essential building blocks (metabolites, amino acids, nucleotides) and macromolecules are discussed (composition, structure). The goal of Biochemistry I is to form a detailed view on membranes, proteins, nucleic acids and organelles of the cell. The biological role of nucleic acids is introduced to allow the discourse of Biochemistry III (molecular biology). The biological role of a number of structural proteins, transport proteins, co-factors and enzymes will be discussed. Enzyme-function en -kinetics will be thoroughly introduced.
In a second part, Biochemistry II-‘Metabolism’, our attention shifts to the cellular metabolism, with emphasis on glucose- and fatty acids. Anabolism, catabolism, energy-metabolism, and basic metabolic pathways will be dealt with.
The Biochemistry I-II course is subdivided into clearly delineated (chapter-like) learning units and is partly conceptual and partly descriptive.

Course material
Digital course material (Required) : Powerpoint presentaties met extra figuren zijn beschikbaar, M. Van de Casteele, Canvas
Course text (Required) : Biochemie, Biomoleculen & Metabolisme, M. Van de Casteele, VUB, 2220170000480, 2015
Handbook (Recommended) : Leerboek metabolisme, F. Schuit, 2de herziene drukste druk, Bohn Stafleu Van Loghum – Houten, Nederland, 9789036806190, 2015
Handbook (Recommended) : Molecular Biology of the Cell, B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter, 6de, Garland, 9780815344643, 2014
Additional info

Lecture notes with figures are available (Pointcarré).

Complementary material:
Suggested textbooks:

B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter: “Molecular Biology of the Cell”, Fifth Edition, Garland Science, 2008.

“Metabolisme”, F.C. Schuit, Bohn Stafleu Van Loghum – Houten, Nederland, First edition (Dutch), 2010.

Learning Outcomes

General competencies

Biochemistry is an important basis for education and research in Pharmaceutical Sciences. The biochemical approach to the study of 'health and disease of the human body' is supported by an intense scientific progress in this area, based upon equally important developments in modern biology and chemistry.
Biochemistry is lectured early-on in the first semester of the 2nd Bachelor year of the Pharmaceutical Sciences.   This is complemented by a rather extensive set of lab practicals. Biochemistry is then further deepened in the second semester.
In the first package (Biochemistry I-II) students are expected to gather essential knowledge of 'facts' and acquire an understanding of biochemical concepts (structure, bio-catalysis, dynamics, kinetics).

Grading

The final grade is composed based on the following categories:
Written Exam determines 100% of the final mark.

Within the Written Exam category, the following assignments need to be completed:

  • Schriftelijk examen with a relative weight of 1 which comprises 100% of the final mark.

    Note: Kennis en inzicht van de student(e) in de leerstof van de hoorcolleges wordt getoetst via een schriftelijk examen (deels meerkeuzevragen, deels korte open vragen).

Additional info regarding evaluation

Knowledge and understanding of the subject are assessed through a written exam (partly multiple choice, partly open questions).

Allowed unsatisfactory mark
The supplementary Teaching and Examination Regulations of your faculty stipulate whether an allowed unsatisfactory mark for this programme unit is permitted.

Academic context

This offer is part of the following study plans:
Bachelor of Pharmaceutical Sciences: default (only offered in Dutch)
Bachelor of Pharmaceutical Sciences: Verkort traject (only offered in Dutch)