3 ECTS credits
80 u studietijd
Aanbieding 1 met studiegidsnummer 4012687ENR voor alle studenten in het 1e semester met een verdiepend master niveau.
In this course, students will gain deeper insights into the sensing and regulatory mechanisms that enable microorganisms to respond to changes in cell physiology and in the environment. These principles are looked at from the point of signal reception and transduction, down to the level of the resulting transcriptional, post-transcriptional and post-translational responses and finally to the changes in cellular physiology. Molecular mechanisms will be studied across different phylogenetic lineages (grampositive and gramnegative bacteria, archaea, eukaryal microorganisms). The course is divided into two partims: "Molecular regulation in microbial cells” (Prof. Dr. Ir. Eveline Peeters) and "Microbial physiology” (Prof. Dr. Han Remaut). In the first partim, the following topics will be discussed: transcription factors, two-component and phosphorelay signal transduction, alternative sigma factors, small regulatory RNAs, chemotaxis, quorum sensing and biofilm formation. In the second partim, the following topics are included: cell division, cell polarity, the bacterial cytoskeleton, bacterial defense/offense mechanisms, protein folding, thiol redox pathways and unfolded protein response. Throughout the course, students will gain an overview of the main research methodologies used in typical molecular microbiology studies, such that they can workout experimental approaches to test and validate research hypotheses.
Students need to pass for both partims in order to pass for the course. In case a score < 10/20 is obtained for one of the two partims and the average score is > 10/20, the final score corresponds to the lowest partim score. However, students obtain an exemption for every partim with a score > 10/20 and will only need to retake the failed partim exam(s).
Students can explain the molecular mechanisms and principles of (complex) regulatory responses and physiological processes in microbial cells.
Students can describe research methodologies used in molecular microbiology and can propose experimental approaches to test and validate research hypotheses.
Students can critically analyze original research papers in the field of molecular microbiology and can formulate the major research hypothesis, significance and key conclusions from each of these papers.
De beoordeling bestaat uit volgende opdrachtcategorieën:
Examen Mondeling bepaalt 100% van het eindcijfer
Binnen de categorie Examen Mondeling dient men volgende opdrachten af te werken:
Not applicable.
Deze aanbieding maakt deel uit van de volgende studieplannen:
Master in de bio-ingenieurswetenschappen: cel- en genbiotechnologie: medische biotechnologie
Master in de bio-ingenieurswetenschappen: cel- en genbiotechnologie: moleculaire biotechnologie
Master in de bio-ingenieurswetenschappen: cel- en genbiotechnologie: agrobiotechnologie
Master in de bio-ingenieurswetenschappen: chemie en bioprocestechnologie: voedingsbiotechnologie
Master in de bio-ingenieurswetenschappen: chemie en bioprocestechnologie: chemische biotechnologie
Master in de bio-ingenieurswetenschappen: chemie en bioprocestechnologie: biochemische biotechnologie
Master of Molecular Biology: Standaard traject (enkel aangeboden in het Engels)
Master in de biologie: moleculaire en cellulaire biowetenschappen
Master in de biologie: ecologie en biodiversiteit
Master in de biologie: onderwijs
Master of Biology: Molecular and Cellular Life sciences (enkel aangeboden in het Engels)
Master of Biology: Human Ecology (enkel aangeboden in het Engels)
Educatieve master in de wetenschappen en technologie: biologie (120 ECTS, Etterbeek)