9 ECTS credits
235 h study time
Offer 1 with catalog number 1017330BNR for all students in the 1st semester at a (B) Bachelor - advanced level.
This Biochemistry course provides an introduction to the molecular design of life. First, we describe the molecular structure of nucleic acids, proteins and explain replication, transcription and translation. Next we discribe biological membranes.
In a second part, we focus on the structure-function relation of proteins: Enzymatic activity (Lysozyme, RNase A, Chymotrypsine, ...), Coöperativity (Hemoglobine en ATCase), enzyme regulation and protein folding.
The last part of the course describes the metabolismof living animals including the key anabolic and catabolic patways (glycolysis, Krebbs cycle, oxidative fosforylation, glycogen metabolism, fatty acid metabolism, pentose phosphate patway, gluconeogenesis).
For the bio-engineers we also teach the metabolism of aminoacids and nucleic acids
.
Aim of the course
The students have a conceptual insight in the molecular basis of life. If possible, we teach these concepts using experimental results to train the students with the experimental approaches of the molecular biologist, biophysist, geneticist, ...
Troughout the course we aim at integrating the different subjects of the program. For example, ATCase, a key enzyme in the metabolism of nucleotides is also used as an example to describe the allosteric feedback regulation of enzymes.
Competences aimed at
The students shoud be able to:
The final grade is composed based on the following categories:
Oral Exam determines 100% of the final mark.
Within the Oral Exam category, the following assignments need to be completed:
The examination ivolves a discussion between the student and the examinator, based on a written preparation by the student
Representative questions include:
- Write down the covalent structure of the peptide Lys Ala His Val. What is the net charge of this peptide at pH5 ?
- Decribe the cooperative properties of hemoglobin.
- Describe the process of transcription
- Describe the oxidative part of the oxidative phosphorylation
This offer is part of the following study plans:
Bachelor of Bioengineering Sciences: Profile Cell and Gene Biotechnology (only offered in Dutch)
Bachelor of Bioengineering Sciences: Profile Chemistry and Bioprocess Technology (only offered in Dutch)
Bachelor of Bioengineering Sciences: Initial track (only offered in Dutch)